This is part III of “Are You Getting Enough Cholesterol?”, part I may be found here, and part II may be found here.
We’re looking at cholesterol, with the help of Chris Masterjohn. His site provides a wealth of material on the science and chemistry of cholesterol, and its impact on health and disease. In this third part, I extract a few interesting facts from Chris’s research, to share, and to inspire you to look further. My own two cents will be indicated by brackets.
-Low blood cholesterol is associated with higher risk of suicide, and by more violent methods than suicides with normal cholesterol levels.

-That those with Smith-Lemli-Opitz Syndrome, or SLOS, cannot properly synthesize cholesterol, and suffer from mental and physical retardation as a result. Those carrying a gene for SLOS, without “having” the disease, have lower synthesis rates than usual, and are at high risk of mental health issues like violence and suicide.
-High cholesterol foods are the only ones with arachidonic acid, the most essential fatty acid. AA can be synthesized from Omega 6 linoleic acid, common in plant foods- but the process is impossible for carnivores like cats, and difficult for omnivores like us. AA has a bad reputation as pro-inflammatory, and as a contributor to arthritis and reproductive ailments- yet it’s vital for hormone regulation. We don’t need much of this particular substance, but we need some! Children, pregnant women, bodybuilders and athletes, and sick people need more. AA deficiency is apparent in hair loss, dry skin and lesions, chronic fatigue and more. There is no AA found in plant foods.
-One reason we need sleep is to let our brain make cholesterol. We need it for learning and memory, and for neuron transmission. A quarter of our brain is made of cholesterol, which is the most important ingredient in forming synapses- i.e. learning, memory, and cognition.
-Cholesterol-lowering drugs cause memory problems, as do low-fat diets, by depriving the brain of cholesterol. Memory concerns are listed as a ‘side effect’ on statin drugs. Adding eggs to the diet improves memory and cognitive functioning.
-Cholesterol maintains fluid balance of cells and keeps them from “going to mush.”
-Cholesterol is the precursor of Vitamin D. Only animal foods contain Vitamin D. But don’t we get Vitamin D from the sun? Yes- because it synthesizes it from cholesterol. In turn, Vitamin D metabolizes calcium- keeping our bones and teeth healthy. It is also important in blood sugar regulation (which prevents metabolic problems, obesity, and diabetes, all of which lead to heart disease.) It’s vital to mental health, cancer prevention, and the immune system. Um, why are we told to avoid the sun, eat a cholesterol-free diet, and take cholesterol-lowering drugs? Clearly, it’s a recipe for disaster that we are already in the midst of. The president of the Vitamin D Council says most whites and nearly all black people are deficient in Vitamin D.
-Cod liver oil and lard are high in Vitamin D. We used to use both liberally. Now no one’s heard of cod liver oil and we avoid lard like the plague. (I might interject here that we always hear about the abundant long life and health of the Okinawans. And most of us think they are soy-gobbling vegetarians over there, because that’s what we are told is the reason for their longevity. But they eat raw fish, tons of pork, and use lard in everything.)
-We need cholesterol to make bile, which we need to digest our fat. If we don’t digest fat properly, we don’t get the nutrients we need from it.
-Looks like our friend cholesterol is the mother of our favourite hormones: “Cholesterol is the precursor to a hormone called pregnenolone, which has important functions itself, but is also the precursor to all other steroid hormones. Pregnenolone is converted to progesterone, a sex hormone, which in turn is converted into cortisol, which regulates inflammation and blood sugar, aldosterone, which regulates mineral balance and blood pressure, or testosterone, a type of sex hormone referred to as an androgen, which regulates libido, muscle mass, and plays other roles. In females, and to a lesser degree in males, testosterone is further modified, undergoing conversion to estradiol, a different type of sex hormone called an estrogen.” Ummm, pass the red meat and eggs please.
-Liver, and cod liver oils (and grass fed butter, though less) are high in cholesterol, and Vitamin A. Vitamin A is found only in animal foods. (It’s common knowledge that beta-carotene from vegetable foods is a precursor to Vitamin A, so vegans are fine, right? Wrong. To convert it, you need fat, and bile, and bile salts- you guessed it, cholesterol!) Vitamin A is vital to regulating fat tissue, blood sugar, oxidative stress, libido, sexual health, energy, and brain health. Liver foods are also high in B vitamins and a host of other good stuff.
-Get cracking. Eggs contain the perfect balance of amino acids, cholesterol, Vitamins A, D, E and K, selenium, magnesium, calcium…indeed, every known nutrient except for Vitamin C! Eggs would go a long way in solving the world’s problem of malnourishment and starvation (unlike the fairly useless grains, which clearly aren’t working.)
Thanks so much to Chris Masterjohn for his comprehensive work in sharing this vital wealth of information with us. This was just a small sampling of the facts- covered in depth at his site (www.cholesterol-and-health.com). There are even chemistry lessons you can take! ![]()






